10 Best Audio Interfaces With MIDI Input in 2026 for Home Studios and Live Setup

The best audio interface with MIDI input gives you more than clean microphone and instrument recordings—it also connects keyboards, controllers, drum machines, and other MIDI hardware to your computer.

We compared 10 popular models across input count, connectivity, recording quality, monitoring features, and ease of use to help you choose the right fit for your studio or mobile setup.

Best 10 Audio Interface with Midi Input Picks for 2026

Versatile 4-Channel Workhorse – Behringer U-PHORIA UMC404HD

If you need an audio interface with midi input and enough connections for a growing recording setup, the Behringer U-PHORIA UMC404HD is a practical choice. It provides four inputs, four outputs, MIDI I/O, four MIDAS-designed mic preamps, and support for recording at up to 24-bit/192 kHz.

Best For: Home studios recording multiple microphones, instruments, or MIDI hardware at once.

Pros:

• Four-in/four-out design with MIDI input and output.
• Four mic preamps with +48V phantom power for condenser microphones.
• Supports up to 24-bit/192 kHz audio and works with popular recording software.
• Impact-resistant metal chassis is designed for durability.

Cons:

• Its larger four-channel layout may be more than a simple two-input setup needs.
• Uses USB 2.0 rather than USB-C connectivity.

The UMC404HD stands out when connection count matters. Its four analog inputs and dedicated MIDI I/O make it well suited to recording ensembles, hardware synthesizers, and more involved desktop rigs.

Feature-Rich Studio Hub – Focusrite Scarlett 4i4 4th Gen

The Focusrite Scarlett 4i4 4th Gen is a flexible audio interface with midi input for producers working with microphones, instruments, synths, and drum machines. It combines two mic preamps, two Hi-Z inputs, four line inputs, four line outputs, and MIDI I/O with useful level-management features.

Best For: Producers who need multiple line connections, MIDI hardware support, and a broad software bundle.

Pros:

• Offers 4-in/4-out operation with MIDI input and output.
• Includes two mic preamps, two Hi-Z inputs, four line inputs, and four line outputs.
• Auto Gain and Clip Safe help manage recording levels.
• Air mode, 120 dB dynamic range, and 24-bit/192 kHz support add recording flexibility.

Cons:

• Its wider feature set may be unnecessary for basic vocal-and-guitar recording.
• Requires USB-C connectivity and includes a power supply in the package.

With its combination of analog I/O, MIDI, and workflow-focused features, the Scarlett 4i4 is a strong fit for a studio that may expand beyond a couple of direct inputs.

Compact MIDI Recording Choice – Mackie Onyx Producer 2-2

The Mackie Onyx Producer 2-2 is a compact audio interface with midi input for musicians who need a straightforward two-channel recording setup. Its two Onyx mic preamps, combo inputs, zero-latency direct monitoring, and bus-powered USB connection make it suitable for mobile or desktop recording.

Best For: Singer-songwriters and mobile recording setups using two microphones, instruments, or MIDI gear.

Pros:

• Provides two inputs, two outputs, and MIDI I/O in a compact format.
• Combo inputs accept mic, line, and Hi-Z instrument sources.
• Onyx preamps include +48V phantom power for condenser microphones.
• Bus-powered design and zero-latency direct monitoring support convenient recording.

Cons:

• Two analog inputs offer less expansion than four-channel interfaces.
• Its listed warranty is one year.

The Onyx Producer 2-2 keeps the setup simple without omitting MIDI. It is a sensible option when portability, direct monitoring, and two-channel recording are more important than a large number of analog connections.

Simple Artist-Focused Pick – Focusrite Scarlett 2i2 4th Gen

For musicians who want an audio interface with midi input without paying for a larger I/O layout, the Focusrite Scarlett 2i2 4th Gen offers a focused two-channel design. It includes two mic preamps, two Hi-Z instrument inputs, 24-bit/192 kHz support, and recording tools such as Auto Gain, Clip Safe, and Air mode.

Best For: Vocalists, guitarists, and home-recording beginners who use MIDI gear alongside two primary audio inputs.

Pros:

• Two mic preamps and two Hi-Z instrument inputs cover common recording sources.
• Includes MIDI input and output while retaining a compact design.
• Auto Gain and Clip Safe can help prevent poorly set recording levels.
• Offers 120 dB dynamic range, Air mode, and 24-bit/192 kHz recording.

Cons:

• Two audio inputs limit simultaneous microphone and instrument expansion.
• It has fewer line connections than the Scarlett 4i4.

The Scarlett 2i2 4th Gen is best when the priority is a compact interface for vocals, guitar, and occasional MIDI work. Its included software bundle also gives new users a useful starting point for recording.

Flexible Studio Pick – Behringer UMC204HD

For an audio interface with midi input that can handle microphones, instruments, and external hardware, the Behringer UMC204HD offers two combination XLR/TRS inputs, MIDI I/O, and 24-bit/192 kHz recording over USB. Its inserts and multiple playback outputs also give a home studio room to expand.

Best For: Home-studio musicians who need MIDI connectivity, flexible analog routing, and two recording inputs.

Pros:

• Built-in MIDI I/O connects keyboards and other MIDI hardware.
• Two combination XLR/TRS inputs accommodate microphones, instruments, and line-level sources.
• Supports up to 24-bit/192 kHz audio with Midas-designed mic preamps.
• Analog inserts and both TRS and RCA playback options support external equipment.

Cons:

• Only two input channels are available for simultaneous recording.
• Its USB 2.0 connection is less modern than USB-C alternatives.

The UMC204HD is a practical choice when MIDI ports and hands-on routing matter as much as basic recording. It combines useful studio connections with high-resolution conversion in a compact interface.

Vintage-Voiced Compact Pick – Universal Audio Volt 2

The Universal Audio Volt 2 is an audio interface with midi input designed for musicians, podcasters, and streamers who want a compact 2×2 setup. It combines up to 24-bit/192 kHz recording with a Vintage mode inspired by UA’s classic 610 preamps and support for computers and compatible mobile devices.

Best For: Creators who want portable two-channel recording with vintage-style preamp coloration and MIDI connectivity.

Pros:

• Includes MIDI and a 2×2 USB-C interface configuration.
• Vintage mode provides 610 tube-preamp-inspired character.
• Supports up to 24-bit/192 kHz recording and mixing.
• Works with macOS, Windows, iPad, and iPhone, subject to the listed adapter and power requirements.

Cons:

• Mobile iPad and iPhone use may require an external power supply and Apple adapter.
• Its two-channel design is aimed at smaller recording setups.

Volt 2 suits users who value straightforward portability and a distinctive preamp mode. The included software ecosystem and cross-platform support add flexibility for recording and learning.

DSP Monitoring Pick – Yamaha URX22C

For buyers seeking an audio interface with midi input and low-latency monitoring, the Yamaha URX22C pairs two combo inputs with MIDI I/O, 32-bit integer/192 kHz support, and DSP-powered effects. Its full-metal housing and cross-platform compatibility make it a strong fit for a durable desktop setup.

Best For: Musicians who want built-in monitoring effects, Hi-Z instrument support, and a rugged two-input interface.

Pros:

• Provides MIDI I/O alongside two analog inputs and two main outputs.
• Class-A D-PRE preamps include +48 V phantom power.
• DSP-powered monitoring includes REV-X reverb, Channel Strip, and Guitar Amp Classics.
• Supports 32-bit integer/192 kHz audio and Windows, macOS, and iOS devices.

Cons:

• It offers two input channels, which may limit larger recording sessions.
• The included software and DSP features may be more than needed for basic recording.

The URX22C stands out for combining MIDI, durable construction, and latency-free DSP monitoring in a compact 2-in/2-out format. It is especially appealing to guitarists and vocalists who want effects while tracking.

Classic UA Character – Universal Audio Volt 1

The Universal Audio Volt 1 is a compact audio interface with MIDI input compatibility for creators who want polished recordings from a microphone, guitar, or MIDI setup. Its Vintage mode, 24-bit/192 kHz support, and compatibility with computers and Apple mobile devices make it flexible for studio or portable recording.

Best For: Singers, instrumentalists, and mobile producers seeking UA preamp character in a compact two-channel interface.

Pros:

• Vintage mode is designed to provide the sound of UA’s classic 610 preamps.
• Supports recording and playback up to 24-bit/192 kHz.
• Works with Mac, Windows, iPad, and iPhone, with appropriate accessories and power requirements.
• Includes access to LUNA and support for UAD plug-ins and instruments.

Cons:

• Requires an external Volt power supply for some setups.
• Apple mobile recording may require a Lightning to USB Camera Adapter.
• Provides two channels, which may be limiting for larger recording sessions.

The Volt 1 is a strong choice when sound character and high-resolution recording matter more than a large input count. It is especially appealing for solo recording and compact MIDI-enabled setups.

Flexible Routing Choice – ESI Amber i1 USB Audio Interface

The ESI Amber i1 is an audio interface with MIDI input compatibility that combines a combo XLR/¼-inch input, RCA connectivity, and USB-C operation. Its 24-bit/192 kHz support, loopback routing, and included software make it a practical option for recording, streaming, podcasting, and instrumental work.

Best For: Guitarists, vocalists, streamers, and producers who need flexible connections and software-based routing.

Pros:

• Offers up to 24-bit/192 kHz resolution for studio-oriented recording.
• Combo XLR/¼-inch TRS input supports microphone and instrument or line signals.
• Includes DirectWIRE loopback for internal audio routing.
• Provides USB-C power, +48V phantom power, a headphone amp, and bundled software.

Cons:

• The two-channel design may not suit users recording many sources simultaneously.
• Its broad feature set may be more than needed for a simple microphone-and-guitar setup.

Choose the Amber i1 if connection flexibility and loopback are priorities. It is well suited to modern computer-based workflows where recording, streaming, and software routing share the same interface.

Budget MIDI Workhorse – PreSonus AudioBox 96

The PreSonus AudioBox 96 is a straightforward audio interface with MIDI input and output for personal or portable recording. It pairs two Class-A mic preamps and instrument inputs with 24-bit/96 kHz conversion, zero-latency monitoring, and USB bus power.

Best For: Home recordists and musicians who want an affordable two-channel interface with MIDI I/O and a substantial software bundle.

Pros:

• Includes two Class-A mic preamps and two high-headroom instrument inputs.
• Provides MIDI I/O for compatible hardware.
• USB bus power supports portable recording without an additional power supply.
• Includes Studio One Artist, Ableton Live Lite, and the Studio Magic Plug-In suite.

Cons:

• Its maximum sample rate is 24-bit/96 kHz rather than 192 kHz.
• Only two input channels are available for simultaneous recording.
• Global +48V phantom power may be less flexible for mixed microphone setups.

The AudioBox 96 focuses on the essentials and adds useful MIDI connectivity without requiring an external power supply. It is a sensible pick for beginners and home studios that value simplicity, portability, and bundled recording software.

How We Picked the Best Audio Interface with Midi Input

We focused on models that combine USB audio recording with practical MIDI connectivity, then compared their I/O, preamp configuration, monitoring controls, driver and software support, and suitability for different workflows. The selection includes compact two-channel interfaces for solo creators, as well as four-input models for small bands, hardware-based production, and more flexible routing.

We also considered recording resolution, connection type, phantom power, direct monitoring, headphone functionality, and whether the interface offers useful extras such as onboard processing or bundled music software. MIDI ports are especially important for anyone using external synthesizers, drum machines, controllers, or vintage hardware.

Quick Comparison

• Best for larger home-studio setups: Behringer U-PHORIA UMC404HD, with four analog inputs and extensive MIDI connectivity.
• Best for modern all-purpose recording: Focusrite Scarlett 4i4 4th Gen, offering flexible I/O and USB-C connectivity.
• Best compact options: Mackie Onyx Producer 2X2, Yamaha 2-in/2-out, and Behringer UMC204HD.
• Best for solo vocalists and instrumentalists: Focusrite Scarlett 2i2 4th Gen, Universal Audio Volt 1, and PreSonus AudioBox 96.
• Best for built-in creative processing: Universal Audio Volt 2 and the Yamaha interface with DSP-powered mixing and effects.

Key Buying Factors for an Audio Interface with Midi Input

Input and Output Count

Two inputs are sufficient for one or two microphones, a stereo keyboard, or a microphone and guitar recorded together. Choose four inputs if you record multiple performers, stereo hardware, or several instruments without constant repatching. Also check the line outputs if you plan to connect studio monitors, an external mixer, or outboard effects.

MIDI Connections and Routing

Confirm that the interface has standard five-pin MIDI In and Out if you need to connect traditional hardware. MIDI does not carry audio, so a synthesizer or drum machine may still need to connect through the interface’s line inputs. Look for convenient MIDI routing and reliable synchronization if you use several external devices.

Audio Quality and Monitoring

24-bit recording and high sample-rate support are common, but preamp quality, gain range, noise performance, and low-latency monitoring matter more in everyday use. Direct monitoring can help you hear yourself without distracting delay, while independent headphone control is useful when recording with another person.

Computer Compatibility and Power

USB-C connectivity may provide a newer physical connection, but confirm included cables and compatibility with your computer or tablet. Bus-powered interfaces are convenient for mobile work; models that require external power can be preferable when running multiple inputs or connected MIDI hardware.

Who Should Buy Which Audio Interface with Midi Input?

Choose a two-input interface if you are a vocalist, guitarist, producer, or keyboard player building a compact setup. Step up to a four-input model if you record bands, multiple microphones, stereo instruments, or several hardware sources. Producers who rely on external synths and drum machines should prioritize standard MIDI ports, dependable line inputs, and enough outputs for monitoring and hardware routing. If you value fast setup and creative effects, consider a model with onboard DSP or voice-focused processing. Finally, prioritize driver stability, monitoring controls, and the number of connections you will actually use rather than choosing solely by maximum sample rate.