Life is full of challenges—some come unexpectedly, others we wrestle with for years. Whether you’re facing heartbreak, failure, illness, or simply feel exhausted, it’s easy to lose hope. But the Bible offers comfort and courage in those moments. God’s Word is filled with reminders that He walks with us, strengthens us, and calls us not to give up.
These carefully selected Bible verses about not giving up are here to remind you that persistence is not just possible—it’s a reflection of faith. God honors endurance, and through His strength, we can press on even when the road is tough.
Below, you’ll find 15 powerful Scriptures that encourage resilience and spiritual grit.
1. Galatians 6:9
Let us not become weary in doing good, for at the proper time we will reap a harvest if we do not give up.
Explanation:
This verse encourages believers to stay faithful in doing what is right, even when results are not immediate. God promises a reward for endurance, reminding us that our efforts are never wasted in His eyes.
2. Isaiah 40:31
But those who hope in the Lord will renew their strength. They will soar on wings like eagles; they will run and not grow weary, they will walk and not be faint.
Explanation:
This beautiful promise highlights how God gives strength to the weary. When we lean on Him, we are renewed—physically, emotionally, and spiritually. We keep going not by our power, but by His.
3. 2 Corinthians 4:8–9
We are hard pressed on every side, but not crushed; perplexed, but not in despair; persecuted, but not abandoned; struck down, but not destroyed.
Explanation:
Paul shares his struggles, but also his confidence in God. These verses show that trials may press us, but they won’t break us when we hold on to our faith. God sustains us through every hardship.
4. Hebrews 12:1
Therefore, since we are surrounded by such a great cloud of witnesses, let us throw off everything that hinders and the sin that so easily entangles. And let us run with perseverance the race marked out for us.
Explanation:
This verse compares life to a race and calls us to run it with perseverance. It reminds us that we’re not alone—others have run before us, and God has a unique path for each of us to follow faithfully.
5. Philippians 4:13
I can do all this through him who gives me strength.
Explanation:
Short but powerful, this verse declares that our strength comes from Christ. No matter what you’re facing, He gives you the power to keep going.
6. Romans 5:3–4
Not only so, but we also glory in our sufferings, because we know that suffering produces perseverance; perseverance, character; and character, hope.
Explanation:
This passage shows that trials serve a purpose. They help shape our faith and build endurance. Even pain can be part of God’s refining process to bring about hope.
7. James 1:12
Blessed is the one who perseveres under trial because, having stood the test, that person will receive the crown of life that the Lord has promised to those who love him.
Explanation:
God honors those who endure. This verse gives eternal perspective—our perseverance today leads to spiritual reward and eternal life with Him.
8. 2 Thessalonians 3:13
And as for you, brothers and sisters, never tire of doing what is good.
Explanation:
We are encouraged not to grow weary in doing good. Even when it’s hard, or when others don’t notice, God sees our faithfulness and encourages us to keep going.
9. Joshua 1:9
Have I not commanded you? Be strong and courageous. Do not be afraid; do not be discouraged, for the Lord your God will be with you wherever you go.
Explanation:
God gives Joshua a direct command: be brave and strong. That same call is for us today. God’s presence is the reason we don’t have to fear or give up.
10. Psalm 27:14
Wait for the Lord; be strong and take heart and wait for the Lord.
Explanation:
Waiting can be the hardest form of perseverance. This verse encourages us to stay strong while we wait, trusting that God’s timing is perfect and His help is coming.
11. Proverbs 24:16
For though the righteous fall seven times, they rise again, but the wicked stumble when calamity strikes.
Explanation:
Even faithful people fall. What matters is getting back up. This verse reminds us that resilience, not perfection, defines a righteous life.
12. Revelation 2:3
You have persevered and have endured hardships for my name, and have not grown weary.
Explanation:
This verse is a commendation from Jesus to a faithful church. It celebrates their endurance and encourages us to keep pressing on for His name.
13. Matthew 11:28–30
Come to me, all you who are weary and burdened, and I will give you rest. Take my yoke upon you and learn from me, for I am gentle and humble in heart, and you will find rest for your souls. For my yoke is easy and my burden is light.
Explanation:
Jesus offers rest for the weary. He invites us to come to Him, not to give up. His way brings peace, even when life feels heavy.
14. 1 Corinthians 15:58
Therefore, my dear brothers and sisters, stand firm. Let nothing move you. Always give yourselves fully to the work of the Lord, because you know that your labor in the Lord is not in vain.
Explanation:
This verse encourages us to stay steady in our service to God. Even when results seem slow, our work has eternal value and will never be in vain.
15. Isaiah 41:10
So do not fear, for I am with you; do not be dismayed, for I am your God. I will strengthen you and help you; I will uphold you with my righteous right hand.
Explanation:
God promises to strengthen and uphold us. When fear tempts us to quit, His presence gives us courage and the power to press on.
Stay Encouraged: Keep Going with Faith
These Bible verses about not giving up remind us that perseverance is not only possible—it’s expected and supported by God Himself. The road might be rough, and the challenges real, but you are never alone. God walks beside you, renews your strength, and equips you to overcome every obstacle.
So don’t quit. Keep showing up. Keep trusting. Keep praying. Let God’s Word be the fuel that carries you forward.
Which verse spoke to your heart today? Share your favorite Bible verses about not giving up in the comments—and encourage someone else who might be struggling.